Personally, I'm not sure. I'll tell about this experience I had not too long ago, though.
I went and looked at this house, the guy said he'd make an excellent deal, dropped the price $20,000 (wow), so I went and looked. It was a really nice house, but one of the back windows was busted out of the door, I could reach right inside and open (I had permission to break in

lol).
Two things in particular got to me.
I stepped inside, and immediately got chills. No, it wasn't because I was alone in a strange house because I'm always alone and DO NOT spook easily. The kitchen was right off of the laundry room (where I came in), and I got so spooked by the basement door (which was locked from the OTHER side, I couldn't get in and didn't want to). I felt like I HAD to get and stay away from that door.
The second was the bedroom closest to the living room. It had a lock on the outside of the door, and could only be unlocked from the outside. The closet door in that room had been ripped off of the hinges and the bricks were showing. I got out of that room fast.
The fireplace spooked me a little too for some reason. To get out of the house I had to pass the basement door again, which I didn't like. I never called the guy back.