Here's somethign I say to offend as many people/groups as possible:

Nuke an unborn femminist gay whale for Jesus.

gg---I have been nicknamed "Irish" since I was a teenager & I
have been a biker since I was 15.I have been called,just about everything.Hardly anything offends me anymore.As a matter,of fact,some of the Irish slurs(?) I take as a compliment.About the only thing,that bothers me,is if someone calls me unpatriotic! Irish

my favorite offensive comment, made by a very twisted friend of mine when someone started discussing concentration camps...

"hey asshole, have some respect, my grandfather died in a concentration camp!"

<embarassed mumbling....awkward condolences>

"yeah, he fell out of a guard tower and broke his neck."